Quantum computing represents a new paradigm that has the potential to transform problems that are computationally intractable today into solvable problems in the future.  Significant advances in the last decade have lent support to the idea that quantum computers can be implemented, and further that the goal of demonstrating true performance advantages over traditional computing techniques on one or more problems may be achieved in the not so distant future. Delivering on this promise is expected to require quantum error correction solutions, in turn demanding large qubit counts that pose significant challenges for quantum computer implementations, especially in the area of qubit interface electronics. An active area of research to address this challenge is the use of integrated cryogenic CMOS designs.  In this presentation, we will present a superconducting qubit-based quantum computing system framework, opportunities for cryogenic CMOS introduction into future systems, example cryogenic CMOS implementations and results, and next challenges that must be met to enable cryogenic CMOS adoption.